50 Cent will be appearing in Spy, a spy comedy film starring Melissa McCarthy, Jude Law, Nia Long and Jason Statham, among others, according to The Hollywood Reporter.
The rapper is slated to portray himself in the film, which is scheduled to shoot in Budapest this month.
50 Cent also recently wrapped filming The Prince, a crime caper starring Bruce Willis and John Cusack.
Last year, 50 Cent appeared in Escape Plan with Sylvester Stallone and Arnold Schwarzenegger.
50 Cent is slated to release his next album, Animal Ambition, June 3. He says Jadakiss is scheduled to appear on "Irregular Heartbeat," a cut off the collection. Prodigy and Styles P are slated to join 50 on "Chase The Paper" and Kidd Kidd is set to be featured on three of the album's songs, including "Every Time I Come Around."