According to the Twitter account of E! News' Michael Yo, the legendary producer will be hooking up with one of Hip Hop's premier artists for his first single: "Look for it this week New Jay Z and Dr Dre!!!" tweeted Yo.
Michael Yo later added that Interscope Records was "buzzing" about the as-of-now unnamed song. According to YouHeardThatNew.com, the track has been described as "up-tempo," and is indeed intended as Detox's first single.
More on this as it develops.